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Acne is a disease of the pilosebaceous follicles and therefore affects the face and upper trunk.In acne grade I open and closed conmedones are the main lesions, which occur mostly in the face. They appear 2 – 3 years before the onset of significant inflammatory lesions (papules and pustules). Open comedones, also called blackheads, occur due to oxidation of melanin.
Acne Comedonica