Acute disease characterized by dark-red and slowly growing painful papules and plaques particularly on the face and the extremities accompanied by high fever and neutrophilic leukocytosis in the blood. The patients are usually women over 30 years of age. The skin lesions are often preceded by an infection in the upper respiratory or gastrointestinal tract. A symptom-free interval of 1 - 3 week is followed by the acute onset of the disorder. However, this is not always the case. Associations with colitis ulcerosa, acute myelogenous leukaemia and other malignancies have also been reported.
Sweet-Syndrom, Akute febrile neutrophile Dermatose