The most common clinical presentation of primary herpesvirus type 1 infection is gingivostomatitis. This herpetic stomatitis presents with multiple vesicles scattered across the oral mucosa and gingiva, followed by round or ovoid confluent ulcers. Fever, anorexia, and enlargement of the cervical lymph nodes may also be present. Oral infection with herpesvirus type 2 is also seen. Herpetic gingivostomatitis resolves spontaneously in 7 - 10 days. Recurrent intraoral herpes simplex infection may occasionally affect apparently healthy individuals, especially at sites of trauma. Chronic herpetic ulcers may be seen in patients with neutropenia, leukaemia or HIV disease.
Herpes Simplex Oralis