Sharply localized, circumscribed plaque that recurs at the same site each time the offending drug is administered. Lesions, which are solitary at first, begin as a pruritic erythematous patch, then become oedematous, and sometimes bullous. As re-exposures occur, lesions often increase in number and size. Causative preparations include phenolphthalein, barbiturates, sulphonamides, oral contraceptives, and tetracycline.
Drug eruption, fixed, DRUG ERUPTIONS, FIXED, Fixed drug eruption, Fixed drug eruption, NOS