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Stevens-Johnson Syndrome

definition

A variant of bullous erythema multiforme usually preceded by a respiratory illness followed after 1-14 days by severe erosions of at least two mucosal surfaces with extensive necrosis of the lips and mouth and a purulent conjunctivitis. Clinical findings range from mild skin and mucous membrane involvement to a severe systemic disorder. Ocular symptoms include ulcerative conjunctivitis, keratitis, iritis, uveitis, and sometimes blindness. Stevens-Johnson syndrome may present with mucosal lesions only or both mucosal and skin lesions. Among the precipitating factors are drugs (NSAIDs, sulphonamides, penicillins) but also infectious agents as mycoplasma pneumoniae, yersinia or other viruses and bacteria.

synonyms

Stevens-Johnson Syndrome, Erythema Exsudativum Multiforme, Major Form, Stevens-Johnson-Fuchs-Syndrome, Syndroma Muco-Cutaneo-Oculare Fuchs, Fiessinger-Rendu-Syndrome, Stevens-Johnson Syndrome

UMLS

ERYTHEMA MULTIFORME EXUDATIVUM, FEBRILE MUCOCUTANEOUS SYNDROME, Stevens - Johnson syndrome, Stevens Johnson Syndrome, STEVENS JONHSON SYNDROME, Stevens-Johnson Syndrome, SYNDROME STEVENS-JOHNSON, Syndrome, Stevens-Johnson

images

10 images found for this diagnose localisation: conjunctiva, angle of the eye, diagnosis: Stevens-Johnson Syndrome localisation: glans penis, diagnosis: Stevens-Johnson Syndrome localisation: lips (skin), diagnosis: Stevens-Johnson Syndrome diagnosis: Stevens-Johnson Syndrome diagnosis: Stevens-Johnson Syndrome localisation: mucous membrane of the mouth, diagnosis: Stevens-Johnson Syndrome diagnosis: Stevens-Johnson Syndrome localisation: lips (skin), eyes, diagnosis: Stevens-Johnson Syndrome localisation: lips (skin), diagnosis: Stevens-Johnson Syndrome localisation: eyes, mucous membranes (oral, nasal), diagnosis: Stevens-Johnson Syndrome